Apelin to GDF15: Understanding Exercise-Derived Signaling Molecules in Modulating Metabolic Health

Apelin to GDF15: Understanding Exercise-Derived Signaling Molecules in Modulating Metabolic Health | Recording

Overview

Watch a 2-speaker webinar to learn about the latest published developments in exercise physiology research. We take an integrative approach as we explore the role of exercise-derived signaling molecules in mediating improvements in metabolic health in obesity and diabetes.

Learning Objectives:

Speaker 1 (Dr. Du):

To understand how obesity in mothers impairs placental and fetal development
To explore how the exerkine, apelin, can improve fetal and placental development and offspring metabolic health

Speaker 2 (Mr. Axelrod):

To overview how exercise positively influences glucose-stimulated insulin secretion through direct interorgan communication between the skeletal muscle and the pancreas
To understand the mechanistic role of skeletal muscle-derived growth differentiation factor 15 (GDF15) in enhancing glucose-stimulated insulin secretion and β-cell function in type 2 diabetes

Speakers

Min Du, PhD
Regents Professor, Laboratory of Nutrigenomics and Growth Biology, Washington State University Pullman
Pullman, WA, USA

Min Du is a Regents Professor in Nutrigenomics and Growth Biology at Washington State University. He obtained his PhD at Iowa State University and postdoc training in Biochemistry at University of Alberta. He started his career at University of Wyoming and later moved to the current institution as a professor and Endowed Chair in Growth Biology. His research focuses on the impacts of maternal nutrition and exercise on fetal and placental development, particularly epigenetic changes associated with the early differentiation of mesenchymal progenitor cells.

Christopher L. Axelrod, MEd
Director, Integrated Physiology and Molecular Metabolism Laboratory Director, Mitochondrial Phenotyping Facility, Pennington Biomedical Research Center
Baton Rouge, LA, USA

Christopher Axelrod is Director of Integrated Physiology and Molecular Medicine and the Mitochondrial Phenotyping Facility at Pennington Biomedical Research Center in Baton Rouge, Louisiana. His research applies a bioenergetic lens to understand the pathogenesis of complex metabolic diseases such as insulin resistance, obesity, and type 2 diabetes, non-alcoholic fatty liver disease, and cancer. Furthermore, his work employs bench to bedside designs to translate research findings into clinically relevant observations that serve as the basis for novel therapeutic strategies.

Moderator

Ryan D. Russell, PhD
Associate Professor of Exercise Science and director of the CardioMetabolic eXercise Lab (CMX-Lab) at University of Texas Rio Grande Valley
Edinburg, TX, USA

Dr. Russell is a tenured Associate Professor of Exercise Science and director of the CardioMetabolic eXercise Lab (CMX-Lab) at University of Texas Rio Grande Valley whose research is focused on identifying the etiologies of cardiometabolic and related diseases. His doctorate work focused on cardiometabolic health disparities noted in people at higher risk for type 2 diabetes (T2D), specifically focusing on metabolic flexibility, and how resistance training reduces disparities in lipid oxidation between populations with stratified risk. Dr. Russell has a total of 5 years postdoctoral experience at 1) the University of Maryland School of Medicine (T32) studying cellular and molecular aspects of cardiometabolic disease, 2) the University of California Los Angeles utilizing continuous glucose monitoring systems to quantify improved glycemic regulation noted with resistance training, and 3) the Menzies Institute for Medical Research studying microvascular regulation of diabetes metabolism. His ongoing cardiometabolic health disparity research builds upon previous training and seeks to identify early pathophysiological mechanisms leading to the development and progression of T2D with specific interest in health disparities noted in high-risk populations. Dr. Russell is the current Director of Communications for the ADA Exercise Physiology Interest Group.

Summary


Availability:	On-Demand


Cost:	FREE


Credit Offered:	No Credit Offered

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